C21
⚠ Non-billable
Malignant neoplasm of anus and anal canal
ICD-10-CM · FY2026 · Neoplasms
Code
C21
System
ICD-10-CM
Billable
No — use specific code
Effective
FY2026
Chapter
Neoplasms
Source
CMS / CDC NCHS
⚠ Verify before billing. Confirm against the current CMS/NCHS ICD-10-CM files and your payer's rules before claims submission.
Frequently asked questions
What is ICD-10 code C21?
ICD-10-CM code C21 represents Malignant neoplasm of anus and anal canal. It is a non-billable header code requiring a more specific subcategory in the Neoplasms chapter, effective October 1, 2025 – September 30, 2026.
Is C21 billable?
No. C21 is a non-billable header. Select a more specific subcategory for claims submission.
What chapter is C21 in?
C21 belongs to the Neoplasms chapter (C00–D49) of ICD-10-CM.
Related codes in the C21 category
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