C22
⚠ Non-billable
Malignant neoplasm of liver and intrahepatic bile ducts
ICD-10-CM · FY2026 · Neoplasms
Code
C22
System
ICD-10-CM
Billable
No — use specific code
Effective
FY2026
Chapter
Neoplasms
Source
CMS / CDC NCHS
⚠ Verify before billing. Confirm against the current CMS/NCHS ICD-10-CM files and your payer's rules before claims submission.
Official coding notes
From CMS's ICD-10-CM Tabular List.
Excludes1 — never code together
- malignant neoplasm of biliary tract NOS (C24.9)
- secondary malignant neoplasm of liver and intrahepatic bile duct (C78.7)
Use additional code
- code to identify:
- alcohol abuse and dependence (F10.-)
- hepatitis B (B16.-, B18.0-B18.1)
- hepatitis C (B17.1-, B18.2)
Frequently asked questions
What is ICD-10 code C22?
ICD-10-CM code C22 represents Malignant neoplasm of liver and intrahepatic bile ducts. It is a non-billable header code requiring a more specific subcategory in the Neoplasms chapter, effective October 1, 2025 – September 30, 2026.
Is C22 billable?
No. C22 is a non-billable header. Select a more specific subcategory for claims submission.
What chapter is C22 in?
C22 belongs to the Neoplasms chapter (C00–D49) of ICD-10-CM.
Related codes in the C22 category
C22.0
Liver cell carcinoma
Billable
C22.1
Intrahepatic bile duct carcinoma
Billable
C22.2
Hepatoblastoma
Billable
C22.3
Angiosarcoma of liver
Billable
C22.4
Other sarcomas of liver
Billable
C22.7
Other specified carcinomas of liver
Billable
C22.8
Malignant neoplasm of liver, primary, unspecified as to type
Billable
C22.9
Malignant neoplasm of liver, not specified as primary or secondary
Billable
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