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D21 ⚠ Non-billable

Other benign neoplasms of connective and other soft tissue

ICD-10-CM · FY2026 · Neoplasms

Code
D21
System
ICD-10-CM
Billable
No — use specific code
Effective
FY2026
Chapter
Neoplasms
Source
CMS / CDC NCHS
⚠ Verify before billing. Confirm against the current CMS/NCHS ICD-10-CM files and your payer's rules before claims submission.

Official coding notes

From CMS's ICD-10-CM Tabular List.

Includes
  • benign neoplasm of blood vessel
  • benign neoplasm of bursa
  • benign neoplasm of cartilage
  • benign neoplasm of fascia
  • benign neoplasm of fat
  • benign neoplasm of ligament, except uterine
  • benign neoplasm of lymphatic channel
  • benign neoplasm of muscle
  • benign neoplasm of synovia
  • benign neoplasm of tendon (sheath)
  • benign stromal tumors
Excludes1 — never code together
  • benign neoplasm of articular cartilage (D16.-)
  • benign neoplasm of cartilage of larynx (D14.1)
  • benign neoplasm of cartilage of nose (D14.0)
  • benign neoplasm of connective tissue of breast (D24.-)
  • benign neoplasm of peripheral nerves and autonomic nervous system (D36.1-)
  • benign neoplasm of peritoneum (D20.1)
  • benign neoplasm of retroperitoneum (D20.0)
  • benign neoplasm of uterine ligament, any (D28.2)
  • benign neoplasm of vascular tissue (D18.-)
  • hemangioma (D18.0-)
  • lipomatous neoplasm (D17.-)
  • lymphangioma (D18.1)
  • uterine leiomyoma (D25.-)

Frequently asked questions

What is ICD-10 code D21?
ICD-10-CM code D21 represents Other benign neoplasms of connective and other soft tissue. It is a non-billable header code requiring a more specific subcategory in the Neoplasms chapter, effective October 1, 2025 – September 30, 2026.
Is D21 billable?
No. D21 is a non-billable header. Select a more specific subcategory for claims submission.
What chapter is D21 in?
D21 belongs to the Neoplasms chapter (C00–D49) of ICD-10-CM.

Related codes in the D21 category

D21.0 Benign neoplasm of connective and other soft tissue of head, face and neck Billable D21.1 Benign neoplasm of connective and other soft tissue of upper limb, including shoulder Non-billable D21.2 Benign neoplasm of connective and other soft tissue of lower limb, including hip Non-billable D21.3 Benign neoplasm of connective and other soft tissue of thorax Billable D21.4 Benign neoplasm of connective and other soft tissue of abdomen Billable D21.5 Benign neoplasm of connective and other soft tissue of pelvis Billable D21.6 Benign neoplasm of connective and other soft tissue of trunk, unspecified Billable D21.9 Benign neoplasm of connective and other soft tissue, unspecified Billable

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