D57.81
⚠ Non-billable
Other sickle-cell disorders with crisis
ICD-10-CM · FY2026 · Diseases of the Blood and Blood-Forming Organs
Code
D57.81
System
ICD-10-CM
Billable
No — use specific code
Effective
FY2026
Chapter
Diseases of the Blood and Blood-Forming Organs
Source
CMS / CDC NCHS
⚠ Verify before billing. Confirm against the current CMS/NCHS ICD-10-CM files and your payer's rules before claims submission.
Frequently asked questions
What is ICD-10 code D57.81?
ICD-10-CM code D57.81 represents Other sickle-cell disorders with crisis. It is a non-billable header code requiring a more specific subcategory in the Diseases of the Blood and Blood-Forming Organs chapter, effective October 1, 2025 – September 30, 2026.
Is D57.81 billable?
No. D57.81 is a non-billable header. Select a more specific subcategory for claims submission.
What chapter is D57.81 in?
D57.81 belongs to the Diseases of the Blood and Blood-Forming Organs chapter (D50–D89) of ICD-10-CM.
Related codes in the D57 category
D57
Sickle-cell disorders
Non-billable
D57.0
Hb-SS disease with crisis
Non-billable
D57.1
Sickle-cell disease without crisis
Billable
D57.2
Sickle-cell/Hb-C disease
Non-billable
D57.3
Sickle-cell trait
Billable
D57.4
Sickle-cell thalassemia
Non-billable
D57.8
Other sickle-cell disorders
Non-billable
D57.00
Hb-SS disease with crisis, unspecified
Billable
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