E72.12
✓ Billable
Methylenetetrahydrofolate reductase deficiency
ICD-10-CM · FY2026 · Endocrine, Nutritional and Metabolic Diseases
Code
E72.12
System
ICD-10-CM
Billable
Yes — valid for submission
Effective
FY2026
Chapter
Endocrine, Nutritional and Metabolic Diseases
Source
CMS / CDC NCHS
⚠ Verify before billing. Confirm against the current CMS/NCHS ICD-10-CM files and your payer's rules before claims submission.
Frequently asked questions
What is ICD-10 code E72.12?
ICD-10-CM code E72.12 represents Methylenetetrahydrofolate reductase deficiency. It is a billable diagnosis code in the Endocrine, Nutritional and Metabolic Diseases chapter, effective October 1, 2025 – September 30, 2026.
Is E72.12 billable?
Yes. E72.12 is a valid billable ICD-10-CM code for insurance claims and clinical documentation.
What chapter is E72.12 in?
E72.12 belongs to the Endocrine, Nutritional and Metabolic Diseases chapter (E00–E89) of ICD-10-CM.
Related codes in the E72 category
E72
Other disorders of amino-acid metabolism
Non-billable
E72.0
Disorders of amino-acid transport
Non-billable
E72.1
Disorders of sulfur-bearing amino-acid metabolism
Non-billable
E72.2
Disorders of urea cycle metabolism
Non-billable
E72.3
Disorders of lysine and hydroxylysine metabolism
Billable
E72.4
Disorders of ornithine metabolism
Billable
E72.5
Disorders of glycine metabolism
Non-billable
E72.8
Other specified disorders of amino-acid metabolism
Non-billable
Search all 98,186 ICD-10-CM codes instantly
Search ICDwise →