R45.4
✓ Billable
Irritability and anger
ICD-10-CM · FY2026 · Symptoms, Signs and Abnormal Clinical and Laboratory Findings
Code
R45.4
System
ICD-10-CM
Billable
Yes — valid for submission
Effective
FY2026
Chapter
Symptoms, Signs and Abnormal Clinical and Laboratory Findings
Source
CMS / CDC NCHS
⚠ Verify before billing. Confirm against the current CMS/NCHS ICD-10-CM files and your payer's rules before claims submission.
Frequently asked questions
What is ICD-10 code R45.4?
ICD-10-CM code R45.4 represents Irritability and anger. It is a billable diagnosis code in the Symptoms, Signs and Abnormal Clinical and Laboratory Findings chapter, effective October 1, 2025 – September 30, 2026.
Is R45.4 billable?
Yes. R45.4 is a valid billable ICD-10-CM code for insurance claims and clinical documentation.
What chapter is R45.4 in?
R45.4 belongs to the Symptoms, Signs and Abnormal Clinical and Laboratory Findings chapter (R00–R99) of ICD-10-CM.
Related codes in the R45 category
R45
Symptoms and signs involving emotional state
Non-billable
R45.0
Nervousness
Billable
R45.1
Restlessness and agitation
Billable
R45.2
Unhappiness
Billable
R45.3
Demoralization and apathy
Billable
R45.5
Hostility
Billable
R45.6
Violent behavior
Billable
R45.7
State of emotional shock and stress, unspecified
Billable
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