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R78 ⚠ Non-billable

Findings of drugs and other substances, not normally found in blood

ICD-10-CM · FY2026 · Symptoms, Signs and Abnormal Clinical and Laboratory Findings

Code
R78
System
ICD-10-CM
Billable
No — use specific code
Effective
FY2026
Chapter
Symptoms, Signs and Abnormal Clinical and Laboratory Findings
Source
CMS / CDC NCHS
⚠ Verify before billing. Confirm against the current CMS/NCHS ICD-10-CM files and your payer's rules before claims submission.

Official coding notes

From CMS's ICD-10-CM Tabular List.

Excludes2 — not included here, but may code together
  • mental or behavioral disorders due to psychoactive substance use (F10-F19)
Use additional code
  • code to identify any retained foreign body, if applicable (Z18.-)

Frequently asked questions

What is ICD-10 code R78?
ICD-10-CM code R78 represents Findings of drugs and other substances, not normally found in blood. It is a non-billable header code requiring a more specific subcategory in the Symptoms, Signs and Abnormal Clinical and Laboratory Findings chapter, effective October 1, 2025 – September 30, 2026.
Is R78 billable?
No. R78 is a non-billable header. Select a more specific subcategory for claims submission.
What chapter is R78 in?
R78 belongs to the Symptoms, Signs and Abnormal Clinical and Laboratory Findings chapter (R00–R99) of ICD-10-CM.

Related codes in the R78 category

R78.0 Finding of alcohol in blood Billable R78.1 Finding of opiate drug in blood Billable R78.2 Finding of cocaine in blood Billable R78.3 Finding of hallucinogen in blood Billable R78.4 Finding of other drugs of addictive potential in blood Billable R78.5 Finding of other psychotropic drug in blood Billable R78.6 Finding of steroid agent in blood Billable R78.7 Finding of abnormal level of heavy metals in blood Non-billable

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