Is Z16.1 a billable ICD-10 code?

No. Z16.1 is a non-billable header code. Use a more specific subcategory for claims.

Z16.1 ⚠ Non-billable

Resistance to beta lactam antibiotics

Q: What is ICD-10 code Z16.1?

ICD-10-CM code Z16.1 stands for "Resistance to beta lactam antibiotics". It is a non-billable header code in the Factors Influencing Health Status chapter, effective FY2026 (Oct 1, 2025 – Sep 30, 2026).

ICD-10-CM · FY2026 · Factors Influencing Health Status

Code

Z16.1

System

ICD-10-CM

Billable

No — use specific code

Effective

FY2026

Chapter

Factors Influencing Health Status

Source

CMS / CDC NCHS

⚠ Verify before billing. Confirm against the current CMS/NCHS ICD-10-CM files and your payer's rules before claims submission.

Frequently asked questions

What is ICD-10 code Z16.1?

ICD-10-CM code Z16.1 represents Resistance to beta lactam antibiotics. It is a non-billable header code requiring a more specific subcategory in the Factors Influencing Health Status chapter, effective October 1, 2025 – September 30, 2026.

Is Z16.1 billable?

No. Z16.1 is a non-billable header. Select a more specific subcategory for claims submission.

What chapter is Z16.1 in?

Z16.1 belongs to the Factors Influencing Health Status chapter (Z00–Z99) of ICD-10-CM.

Related codes in the Z16 category

Z16 Resistance to antimicrobial drugs Non-billable Z16.2 Resistance to other antibiotics Non-billable Z16.3 Resistance to other antimicrobial drugs Non-billable Z16.10 Resistance to unspecified beta lactam antibiotics Billable Z16.11 Resistance to penicillins Billable Z16.12 Extended spectrum beta lactamase (ESBL) resistance Billable Z16.13 Resistance to carbapenem Billable Z16.19 Resistance to other specified beta lactam antibiotics Billable

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