Z16.2
⚠ Non-billable
Resistance to other antibiotics
ICD-10-CM · FY2026 · Factors Influencing Health Status
Code
Z16.2
System
ICD-10-CM
Billable
No — use specific code
Effective
FY2026
Chapter
Factors Influencing Health Status
Source
CMS / CDC NCHS
⚠ Verify before billing. Confirm against the current CMS/NCHS ICD-10-CM files and your payer's rules before claims submission.
Frequently asked questions
What is ICD-10 code Z16.2?
ICD-10-CM code Z16.2 represents Resistance to other antibiotics. It is a non-billable header code requiring a more specific subcategory in the Factors Influencing Health Status chapter, effective October 1, 2025 – September 30, 2026.
Is Z16.2 billable?
No. Z16.2 is a non-billable header. Select a more specific subcategory for claims submission.
What chapter is Z16.2 in?
Z16.2 belongs to the Factors Influencing Health Status chapter (Z00–Z99) of ICD-10-CM.
Related codes in the Z16 category
Z16
Resistance to antimicrobial drugs
Non-billable
Z16.1
Resistance to beta lactam antibiotics
Non-billable
Z16.3
Resistance to other antimicrobial drugs
Non-billable
Z16.10
Resistance to unspecified beta lactam antibiotics
Billable
Z16.11
Resistance to penicillins
Billable
Z16.12
Extended spectrum beta lactamase (ESBL) resistance
Billable
Z16.13
Resistance to carbapenem
Billable
Z16.19
Resistance to other specified beta lactam antibiotics
Billable
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